When it comes to the way Memantine works, its mechanism of action differs from rivastigmine, donepezil, and galantamine. Glutamate is a chemical that takes part in exchanging messages between nerve cells. In patients suffering from Alzheimer’s, glutamate is released in the increased amount because of how the brain cells are damaged. Such excess of the chemical promotes further damage to the brain cells. The purpose of Memantine is to ensure the protection of brain cells by blocking the influence of glutamate. You can buy memantine for Bitcoin at our online pharmacy for the best price.
How does Memantine work? Memantine is an oral drug that is prescribed for the treatment of Alzheimer’s disease. Other drugs that are implemented in the treatment of Alzheimer’s influence acetylcholine, which is one of the neurotransmitters that help the brain cells communication. The medications, such as rivastigmine (Exelone), donepezil (Aricept), tacrine (Cognex), and galantamine (Razadyne), work by inhibiting acetylcholinesterase, which leads to the destruction of acetylcholine.
The influence of Memantine doesn’t depend on acetylcholinesterase and acetylcholine. Glutamate is considered the main excitatory neurotransmitter. Scientists believe that the stimulating influence of glutamate on the nerve cells leads to their degeneration in conditions, such as Alzheimer’s disease. Similarly to other neurotransmitters, the release and production of glutamate occur in the brain. Once it’s released, glutamate transfers to the closest nerve cells and then gets attached to a receptor called N-methyl-D-aspartate (NMDA). Memantine effectively blocks the receptor, thus decreasing the impact of glutamate. It is believed that by inhibiting the NMDA receptor and thus the negative influence of glutamate, the medication can protect the nerve cells from excessive stimulation